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Gyeongshingangjeehwan (GGEx) modulates Body Weights of High Fat induced Obese Male Micro-pigs

Introduction, Materials and Methods, Pictures of Micro-pigs
Gyeongshingangjeehwan (GGEx) modulates Body Weights of
High Fat induced Obese Male Micro-pigs
Hyoeng Geun JANG, Yang Sam JUNG, Hee Young LEE, Sang Dal RHEE1, Gyeong Chul KIM2,
Hoon KIM3, and Soon Shik SHIN

Introduction

We assessed anti-obesity effect of Gyeongshingangjeehwan (GGEx) in high fat induced obese male micro-pigs by using computerized tomography (CT).
Materials and Methods

7 month-old micro-pigs are fed with normal (n=3) or high fat diet (n=18) for 12 weeks. The pig revealed obesity in high fat diet were divided into 2 groups (n=5 each) and vehicle (OMP) and Gyeongshingangjeehwan (GGEx, 616.7 mg/kg/day) were administrated for 1 month. We monitored body weight and food intake, which were compared to normal control group (NMP). After 1 month, visceral fat were measured with computerized tomography
Table 1. The composition of GGEx

Ingredient %
Radix Ophiopogonis 42.86
Radix Platycodi 28.57
Fructus Schisandrae 14.29
Herba Ephedrae 14.28
Total amounts 100

Table 2. Experimental groups

Group Number of head Sex Dose(㎎/㎏ BW)
NMP 3 Male 0
OMP 5 Male 0
GGEx 5 Male 616.7
NMP: Normal micro-pig, OMP: Obese micro-pig, GGEx: Gyeongshingangjeehwan
Pictures of Micro-pigs



NMP: Normal micro-pig


OMP: Obese micro-pig


GGEx: Gyeongshingangjeehwan
micro-pig